Description

Array 2, 20, 22 – Gut-Brain Barrier Health Screen

Provider: Cyrex laboratory

Description

This panel assesses the integrity of both the intestinal and blood-brain barriers and evaluates immune responses associated with small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS). It provides insights into the gut-brain axis and its role in systemic and neurological health.
Targets:
Array 2: Tight junction proteins (occludin, zonulin), actomyosin, lipopolysaccharides (LPS).
Array 20: Blood-brain barrier proteins.
Array 22: Bacterial cytotoxins and cytoskeletal proteins.
Method/Analytes Measured: Enzyme-Linked Immunosorbent Assay (ELISA) detecting IgG, IgA, and IgM antibodies.
Clinical Use: Evaluates intestinal permeability, which can contribute to systemic inflammation and autoimmunity. Assesses the integrity of the blood-brain barrier, aiding in the early detection of neuroinflammatory and neurodegenerative conditions. Identifies immune responses associated with SIBO and IBS, facilitating targeted treatment strategies. Supports the development of comprehensive interventions to restore barrier integrity and manage related health issues.

Test Targets

N/A

Method / Analytes

Method: Enzyme-Linked Immunosorbent Assay (ELISA) detecting IgG, IgA, and IgM antibodies.
Antibody Class: IgG, IgA, IgM

Clinical Use

Evaluates intestinal permeability, which can contribute to systemic inflammation and autoimmunity. Assesses the integrity of the blood-brain barrier, aiding in the early detection of neuroinflammatory and neurodegenerative conditions. Identifies immune responses associated with SIBO and IBS, facilitating targeted treatment strategies. Supports the development of comprehensive interventions to restore barrier integrity and manage related health issues.

Pathology Area

Neurology